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How the Endocrine System Works
Hormones are produced by the glands of the endocrine system and act as chemical messengers in the blood, affecting the functioning of cells. Only certain cells in the body, known as target cells, are receptive to particular hormones.
Hormone receptors are found either exposed on the surface of the cell or within it, depending on the type of hormone. The binding of hormone to receptor triggers a cascade of reactions within the cell that affects virtually every function of the body.
The Chakras are energy vortices of the energy body that comprise part of the energy system. When perfectly open and balanced, one is lead to the experience of a harmonious reality, connection to the Oneness in everything, and ultimately to union with the Divine Consciousness.
Chakras and the Endocrine System

The endocrine system is a complex part of the human body and is still the process of being fully understood. The ductless glands of the endocrine system provide a chemical communication network that controls a huge number of physiological processes. Theosophist writers were the first to observe that the position of the chakras on the body parallels that of the glands of the endocrine system.

The Main Endocrine Glands
Each gland influences the production of particular hormones:
Source: The Chakra Bible by Patricia Mercier